Apply Now: Research Assistant Position at UT Southwestern Medical Center

 

UT Southwestern Medical Center

Research Positions (all levels) Available - Center for Hypothalamic Research to study the Epigenetic Regulation of Appetite

Research Tech II | Research Assistant I & II | Sr. Research Associate | Lab Coordinator | Postdoc

The Heyward Nutritional and Behavioral Epigenetics laboratory in the Center for Hypothalamic Research at the University of Texas Southwestern Medical Center in Dallas, TX has several openings for full-time paid research positions to aid with studying the transcriptional and epigenomic regulation of appetite.

The Heyward Lab's core mission is to understand how neurotoxic insults caused by an obesogenic diet and aging contribute to epigenetically encoded impairments in the properties of cell types in the brain that control appetite and body weight. We study this broad topic by employing a combination of low-input cell-type specific, and single-cell multiomic, genome-wide assessments of gene expression, epigenetic modifications, chromatin accessibility, and transcription factor DNA binding dynamics, as well as mouse genetic and epigenome engineering tools, in vitro and in vivo assessments of transcription factor activation, and animal behavioral assessments.

Qualifications vary by position. All positions will be advised by Dr. Frankie Heyward and will have the opportunity to participate in lab and journal club meetings. Techniques utilized by the lab include:

• snRNA-seq & snATAC-seq

• Cell type-specific bulk CUT&RUN, TRAP-seq, ATAC-seq, and ChIP-seq

• Stereotaxic delivery of viral constructs in the brain to influence gene expression

• Immunofluorescence to study transcription factor (TF) localization

• Flow cytometric assessments of TF nuclear occupancy

• Mouse breeding, husbandry, and behavioral assessments

Candidates highly motivated to pursue a career in STEM or Medicine and interested in conducting more than 1 year of mentored research should apply.

Please reach out to Frankie.Heyward@utsouthwestern.edu for related inquiries.

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